INFO  @ 22 Mar 2026 18:16:44: [35 MB] # read alignment files... 
INFO  @ 22 Mar 2026 18:16:44: [35 MB] # read treatment tags... 
INFO  @ 22 Mar 2026 18:16:44: [55 MB] Detected format is: BAM 
INFO  @ 22 Mar 2026 18:16:44: [55 MB] * Input file is gzipped. 
INFO  @ 22 Mar 2026 18:16:47: [66 MB]  1000000 reads parsed 
INFO  @ 22 Mar 2026 18:16:50: [73 MB]  2000000 reads parsed 
INFO  @ 22 Mar 2026 18:16:53: [75 MB]  3000000 reads parsed 
INFO  @ 22 Mar 2026 18:16:56: [76 MB]  4000000 reads parsed 
INFO  @ 22 Mar 2026 18:16:59: [85 MB]  5000000 reads parsed 
INFO  @ 22 Mar 2026 18:17:02: [88 MB]  6000000 reads parsed 
INFO  @ 22 Mar 2026 18:17:06: [91 MB]  7000000 reads parsed 
INFO  @ 22 Mar 2026 18:17:09: [105 MB]  8000000 reads parsed 
INFO  @ 22 Mar 2026 18:17:12: [108 MB]  9000000 reads parsed 
INFO  @ 22 Mar 2026 18:17:15: [108 MB]  10000000 reads parsed 
INFO  @ 22 Mar 2026 18:17:18: [112 MB]  11000000 reads parsed 
INFO  @ 22 Mar 2026 18:17:21: [112 MB]  12000000 reads parsed 
INFO  @ 22 Mar 2026 18:17:24: [132 MB]  13000000 reads parsed 
INFO  @ 22 Mar 2026 18:17:26: [132 MB] 13593309 reads have been read. 
INFO  @ 22 Mar 2026 18:17:26: [132 MB] tag size is determined as 99 bps 
INFO  @ 22 Mar 2026 18:17:26: [132 MB] # tag size = 99 
INFO  @ 22 Mar 2026 18:17:26: [132 MB] # total tags in alignment file: 13593309 
INFO  @ 22 Mar 2026 18:17:26: [132 MB] # Build Peak Model... 
INFO  @ 22 Mar 2026 18:17:26: [132 MB] #2 looking for paired plus/minus strand peaks... 
INFO  @ 22 Mar 2026 18:17:29: [147 MB] #2 Total number of paired peaks: 56 
WARNING @ 22 Mar 2026 18:17:29: [147 MB] #2 MACS3 needs at least 100 paired peaks at + and - strand to build the model, but can only find 56! Please make your MFOLD range broader and try again. If MACS3 still can't build the model, we suggest to use --nomodel and --extsize 147 or other fixed number instead. 
WARNING @ 22 Mar 2026 18:17:29: [147 MB] #2 Process for pairing-model is terminated! 
WARNING @ 22 Mar 2026 18:17:29: [147 MB] # Can't find enough pairs of symmetric peaks to build model!